Table 46c: Leading Causes of Premature Death (Prior to Age 65) and Years of Life Lost, New York City - 2022

Cause of Death Total1 Male Female
Deaths YLL2 Deaths YLL2 Deaths YLL2
Total 16,049 249,615 10,392 165,110 5,655 84,375
Acquired Immune Deficiency Syndrome (AIDS) 196 3,265 141 2,443 55 822
Malignant Neoplasms 2,923 30,936 1,442 15,509 1,481 15,427
   Buccal Cavity and Pharynx 67 689 48 484 19 205
   Digestive Organs and Peritoneum 944 9,318 546 5,505 398 3,813
   Respiratory System 469 3,369 291 2,097 178 1,272
     Trachea, Bronchus and Lung 441 3,062 268 1,858 173 1,204
   Breast 330 3,725 2 26 328 3,699
   Genital Organs 321 2,880 76 556 245 2,324
   Urinary Organs 85 814 65 674 20 140
   Other and Unspecified Sites 474 6,884 271 4,101 203 2,783
   Lymphatic and Hematopoietic Tissues 233 3,257 143 2,066 90 1,191
Diabetes Mellitus 462 5,431 282 3,217 180 2,214
Diseases of the Circulatory System 3,789 39,143 2,578 26,696 1,211 12,447
   Diseases of the Heart 3,073 30,361 2,132 21,268 941 9,093
     Hypertension with Heart Disease 638 6,998 433 4,826 205 2,172
     Acute Myocardial Infarction 278 2,707 202 2,086 76 621
     Other Ischemic Heart Diseases+ 1,679 13,802 1,204 10,020 475 3,782
     Other Diseases of the Heart 478 6,854 293 4,336 185 2,518
   Hypertension with or without Renal Disease 155 1,408 95 893 60 515
   Cerebrovascular Disease 404 4,791 248 2,898 156 1,893
   Other Diseases of the Circulatory System 157 2,583 103 1,637 54 946
Pneumonia 249 2,959 145 1,755 104 1,204
Chronic Lower Respiratory Disease (CLRD) 224 2,851 117 1,463 107 1,388
Cirrhosis of Liver 350 4,842 263 3,661 87 1,181
Congenital Anomalies 137 6,820 71 3,507 65 3,248
Certain Conditions Originating in the Perinatal Period 170 10,980 98 6,308 71 4,607
Unintentional Injuries (Total) 3,099 61,783 2,396 47,224 703 14,559
   Motor Vehicle 258 6,961 191 5,031 67 1,930
   Drownings 34 1,153 28 850 6 303
   Falls 123 2,003 105 1,770 18 233
   Poisonings 2,439 45,811 1,892 35,410 547 10,401
Suicide 468 11,759 340 8,611 128 3,148
Homicide and Legal Intervention 427 13,448 353 11,206 74 2,242
COVID-19 734 8,197 435 4,843 299 3,354
All Other Causes 2,821 47,201 1,731 28,667 1,090 18,534

1 Total Deaths include deaths with sex "Not Stated".

2 Years of Life Lost (YLL) is calculated by subtracting age at death from 65.