Table 46c: Leading Causes of Premature Death (Prior to Age 65) and Years of Life Lost, New York City - 2023

Cause of Death Total1 Male Female
Deaths YLL2 Deaths YLL2 Deaths YLL2
Total 14,942 234,578 9,669 153,859 5,272 80,711
Acquired Immune Deficiency Syndrome (AIDS) 172 2,758 125 2,143 47 615
Malignant Neoplasms 3,000 31,323 1,424 13,839 1,576 17,484
   Buccal Cavity and Pharynx 59 603 42 427 17 176
   Digestive Organs and Peritoneum 977 9,141 575 5,245 402 3,896
   Respiratory System 433 3,193 242 1,678 191 1,515
     Trachea, Bronchus and Lung 408 3,029 224 1,557 184 1,472
   Breast 319 3,862 2 8 317 3,854
   Genital Organs 381 3,567 80 569 301 2,998
   Urinary Organs 90 907 64 616 26 291
   Other and Unspecified Sites 514 6,867 282 3,638 232 3,229
   Lymphatic and Hematopoietic Tissues 227 3,183 137 1,658 90 1,525
Diabetes Mellitus 443 5,283 290 3,502 153 1,781
Diseases of the Circulatory System 3,511 35,127 2,443 24,218 1,068 10,909
   Diseases of the Heart 2,800 26,891 1,975 18,883 825 8,008
     Hypertension with Heart Disease 524 5,632 362 3,961 162 1,671
     Acute Myocardial Infarction 266 2,464 203 1,907 63 557
     Other Ischemic Heart Diseases+ 1,560 12,701 1,139 9,458 421 3,243
     Other Diseases of the Heart 450 6,094 271 3,557 179 2,537
   Hypertension with or without Renal Disease 164 1,466 104 926 60 540
   Cerebrovascular Disease 380 4,642 240 2,932 140 1,710
   Other Diseases of the Circulatory System 167 2,128 124 1,477 43 651
Pneumonia 194 2,454 119 1,380 74 1,066
Chronic Lower Respiratory Disease (CLRD) 240 2,928 121 1,663 119 1,265
Cirrhosis of Liver 323 4,578 234 3,432 89 1,146
Congenital Anomalies 149 7,245 72 3,630 77 3,615
Certain Conditions Originating in the Perinatal Period 170 10,951 94 6,072 76 4,879
Unintentional Injuries (Total) 3,049 60,160 2,326 45,417 723 14,743
   Motor Vehicle 255 7,100 202 5,702 53 1,398
   Drownings 29 1,158 24 1,008 5 150
   Falls 131 2,037 105 1,653 26 384
   Poisonings 2,449 45,303 1,858 33,903 591 11,400
Suicide 442 11,292 310 7,912 132 3,380
Homicide and Legal Intervention 394 12,303 337 10,555 57 1,748
COVID-19 111 1,716 67 1,036 44 680
All Other Causes 2,744 46,460 1,707 29,060 1,037 17,400

1 Total Deaths include deaths with sex "Not Stated".

2 Years of Life Lost (YLL) is calculated by subtracting age at death from 65.