Post-Exposure Prophylaxis (PEP)
For Clinicians
CEI Line - 866-637-2342 - provided by the NYSDOH Clinical Education Initiative, New York State medical providers can use this toll-free number to speak with an experienced clinician regarding PrEP, PEP, HIV, HCV, Sexual Health and Drug User health management.
- Provider Directory
- Find providers in your area who offer services including PrEP or PEP
- If you are a provider and want to be included in the directory, go to:
New York State Department of Health AIDS Institute Guidelines and Resources
- Dear Colleague Letter: Rapid Action Needed in the Provision of PEP to Emergency Responders (December 2024) (PDF)
- Dear Colleague letter: 2022 PrEP Update (PDF)
- Dear Colleague letter: PEP to Prevent HIV Infection (October 2020) (PDF)
- NYSDOH Clinical Guidelines: PEP To Prevent HIV Infection (June 2020)
- Employer Responsibilities in PEP Management to Prevent HIV Infection Following an Occupational Exposure (June 2020)
- Dear CEO Letter: Sexual Assault Law effective 6/15/2020, Including Updated HIV PEP Guidance (June 2020, reviewed and updated 2024)
- Dear Colleague Letter: Sexual Assault Law effective 6/15/2020, Including Updated HIV PEP Guidance June 2020, reviewed and updated 2024)
- Occupational Exposure and HIV Testing: Fact Sheet and Frequently Asked Questions (December 2023) (PDF)
Addressing the Cost
- Payment Options for Adults and Adolescents for Post-Exposure Prophylaxis Following Sexual Assault (April 2025) (PDF)
- Payment Options for Adolescents and Adults for Post-Exposure Prophylaxis for All Other Non-Occupational Exposures (May 2025) (PDF)
Doxycycline Post-Exposure Prophylaxis to Prevent Bacterial Sexually Transmitted Infections (STIs)
- New York State Guidelines: Doxycycline Post-Exposure Prophylaxis to Prevent Bacterial Sexually Transmitted Infections
- New York State Office of Sexual Health and Epidemiology for additional resources for providers
Coding for PEP Reimbursement
- Pre-Exposure Prophylaxis (PrEP), Post-Exposure Prophylaxis (PEP), and Other HIV Prevention Strategies: Billing and Coding Guide (October 2023)
New York City Department of Health & Mental Hygiene
Centers for Disease Control and Prevention (CDC)
- Antiretroviral Postexposure Prophylaxis After Sexual, Injection Drug Use, or Other Nonoccupational Exposure to HIV (May 2025)
- 2025 US Public Health Service Guidelines for the Management of Occupational Exposures to Human Immunodeficiency Virus and Recommendations for Post-exposure Prophylaxis in Healthcare Settings (September 2025)
