Post-Exposure Prophylaxis (PEP)
Exposure to HIV is a Medical Emergency
If you think you were exposed to HIV, talk to a medical professional about Post-exposure Prophylaxis (PEP) as soon as possible. You can:
- Call the NYS or NYC PEP hotline:
- Outside NYC: 844-PEP4NOW (844-737-4669)
- In NYC: 844-3-PEPNYC (844-373-7692)
- Talk with your primary care provider right away and ask if they can provide PEP.
- Go to the local emergency room right away. The PEP Can Prevent HIV if You Act Fast fact sheet has information about PEP and what to expect when you go for a PEP evaluation. Print this fact sheet and bring it with you to the emergency room.
PEP is a medicataion that can prevent you from getting HIV after a possible exposure. PEP is effective when started as early as possible, but not later than 72 hours after the exposure.
For more information about PEP, see:
Information for Individuals Who May Have Been Exposed to HIV
- Provider Directory
- Find providers in your area who offer services including PrEP or PEP
New York State Department of Health AIDS Institute
- PEP Patient Follow-Up Guide (June 2025) (PDF)
- I Might Have Been Exposed to HIV.... What Should I Do? (June 2023) (PDF)
Addressing the Cost
- Payment Options for Adults and Adolescents for Post-Exposure Prophylaxis Following Sexual Assault (April 2025) (PDF)
- Payment Options for Adolescents and Adults for Post-Exposure Prophylaxis for All Other Non-Occupational Exposures (May 2025) (PDF)
Medication Information
- Truvada® (emtricitabine/tenofovir disoproxil fumarate)
- Cimduo (tenofovir + lamivudine)
- Isentress® (raltegravir)
- Tivicay (dolutegravir)
- Biktarvy (bictegravir/emtricitabine/tenofovir alafenamide)
Access to New Sterile Syringes and Syringe Disposal
New York City Department of Health & Mental Hygiene
Condoms - You Need These as Well if You are Sexually Active
HIV.gov
- PEP Questions and Answers (July 2025)
